Fibrinogen links vascular pathology to cognitive decline
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چکیده
منابع مشابه
Increased levels of cerebrospinal fluid JNK3 associated with amyloid pathology: links to cognitive decline.
BACKGROUND Alzheimer disease is characterized by cognitive decline, senile plaques of β-amyloid (Aβ) peptides, neurofibrillary tangles composed of hyperphosphorylated τ proteins and neuronal loss. Aβ and τ are useful markers in the cerebrospinal fluid (CSF). C-Jun N-terminal kinases (JNKs) are serine-threonine protein kinases activated by phosphorylation and involved in neuronal death. METHOD...
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ژورنال
عنوان ژورنال: Nature Reviews Neurology
سال: 2019
ISSN: 1759-4758,1759-4766
DOI: 10.1038/s41582-019-0154-8